Published evidence from PubMed.
Localized evidence synthesis for every regulatory market.

Regulatory evidence packages require the same published literature synthesized and accurately localized for each jurisdiction. Claude retrieves relevant systematic reviews from PubMed via MCP, and Lara Translate localizes the evidence synthesis for each regulatory market with your regulatory terminology preserved exactly.

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Claude
PubMed
PubMed
Lara Translate
Claude
200+
Localized evidence synthesis

From PubMed evidence to localized regulatory synthesis for every market.

Claude queries PubMed via MCP and retrieves systematic reviews and meta-analyses relevant to the evidence package: efficacy data, safety profiles, and comparator studies. The evidence synthesis is structured for regulatory submission use. Lara Translate localizes using Faithful style, preserving regulatory terminology and quantitative data exactly for each jurisdiction.

1

Ask Claude to retrieve systematic reviews from PubMed

Claude connects to PubMed via MCP and retrieves systematic reviews and meta-analyses matching the specified clinical question, indication, population, intervention, and comparator. It returns full abstracts, PICO elements, and pooled outcome data for each publication.

Prompt used:"Search PubMed for systematic reviews and meta-analyses published 2018-2024 evaluating [intervention] versus [comparator] in [population] with [indication]. Retrieve the 12 most relevant results. Extract: pooled efficacy outcomes with effect sizes and heterogeneity measures, safety data with incidence rates, and PICO characteristics. Structure a comparative evidence synthesis and translate into German using Lara Translate with Faithful style and the regulatory affairs glossary."
2

PubMed returns 12 systematic reviews with pooled outcome data

PubMed returns all 12 publications with their pooled efficacy estimates, heterogeneity statistics, and safety outcome tables. Claude structures the extracted data into a comparative evidence synthesis organized by outcome domain and evidence quality.

3

Lara Translate localizes the evidence synthesis into German

Lara Translate localizes the evidence synthesis into German using Faithful style, regulatory terminology preserved exactly, pooled effect estimates and confidence intervals treated as non-translatable units. The regulatory affairs glossary enforces approved German translations for evidence grading terms, outcome descriptors, and statistical terminology used in European regulatory documentation.

4

The DACH regulatory team receives a complete German evidence synthesis

The DACH regulatory affairs team receives a structured German document: 12 systematic reviews with pooled efficacy outcomes, safety data with incidence rates, comparator evidence tables, and an evidence quality overview. The synthesis is ready for internal review and briefing, with the same evidence base as every other regional regulatory team.

Why translating individually retrieved PubMed abstracts is not an evidence synthesis

Translating 12 PubMed abstracts produces 12 translated abstracts, not a comparative evidence synthesis. The regulatory affairs team still needs to extract pooled estimates, compare heterogeneity across reviews, assess evidence quality, and produce a structured synthesis document. Claude does that extraction and structuring from the full PubMed results before Lara Translate localizes the output, so the DACH team receives a ready-to-use German synthesis, not a folder of translated abstracts.

What makes a localized evidence synthesis reliable in a regulatory submission.

An evidence synthesis with paraphrased efficacy data or inconsistent regulatory terminology creates submission risk. These four properties prevent that.

Regulatory terminology consistent across every jurisdiction

Efficacy endpoints, safety terminology, and regulatory vocabulary stay consistent across every localized evidence synthesis. Translation memory reuses your approved regulatory phrasing.

Faithful style for all regulatory evidence

Faithful translation preserves efficacy data, safety profiles, and comparator evidence exactly. No paraphrase — every regulatory finding means what the publication said.

Evidence and regulatory context preserved without abstraction

A specific efficacy finding or safety threshold carries precise regulatory meaning in each jurisdiction. You pass the jurisdiction and domain, and Lara Translate localizes accordingly.

Localized evidence synthesis for every regulatory market in one session

In any of 203 languages. Jurisdiction-ready without separate regulatory review of each translation.

Claude + PubMed vs.
Claude + PubMed + Lara Translate

What you needClaude + PubMedClaude + PubMed + Lara Translate
Regulatory terms matching jurisdiction-specific documentationNo controlled vocabulary. MeSH terms and clinical terminology may be rendered inconsistently.Regulatory glossary aligns terms with market-specific standards
Pooled statistics preserved exactly, no approximationNo style mode. Patient-facing summaries and peer-review abstracts get the same generic treatment.Faithful style, all quantitative parameters preserved exactly
Evidence quality grading preserved with exact characterizationP-values, dosage data, and statistics may be paraphrased rather than preserved verbatim.Evidence grading treated as Faithful content, exact wording
Literature retrieved and synthesized in one sessionEach PubMed abstract requires manual processing per language.Claude retrieves, structures, and localizes in one conversation
All regional regulatory teams from the same evidence baseNo translation memory. Repeated clinical terms are not aligned across studies or reviews.200 languages, same session, same regulatory glossary applied

Ready to give every regional regulatory team the same evidence base in their language?

One PubMed query. A structured, localized evidence synthesis for every market in under 5 minutes.

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Tell us your stack and what you want to ship. We'll help you wire your AI assistant to the right tools and Lara Translate so the output lands in every language your team works in — terminology enforced, tone matched.

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